J Immunological Sci. 2019, 3, 14-20.
Comprehensive evaluation of the expressed CD8+ T cell epitope space using high-throughput epitope mapping.
Front. Immunol. 2019, April 26
Methods in Molecular Biology, 3rd Edition, (CH 10). 2018, 1808, 115-132.
Methods in Molecular Biology, 3rd Edition, (CH. 8). 2018, 1808, 85-94.
Methods in Molecular Biology, 3rd Edition, (CH.7). 2018, 1808, 73-84
Methods in Molecular Biology,3rd Edition,(CH 5.) 2018, 1808, 51-62
Multiplexing T- and B-cell FLUOROSPOT assays: Experimental validation of the multi-color ImmunoSpot® Software based on center of mass distance algorithm.
Methods in Molecular Biology, 3rd Edition (CH 9). 2018, 1808, 95-114.
J. Immunology. 2018, 15, 2927-2940.
Acta Neuropathologica. 2017, 134, 281-295.
Cancer Immunology, Immunotherapy. 2016, 65, 847-855.
Cells. 2015, 4, 71-83.
Characterization of the HCMV-specific CD4 T cell responses that are associated with protective immunity.
Cells. 2015, 7, 4414-4437.
Identification of a B cell-dependent subpopulation of multiple sclerosis by measurements of brain-reactive B cells in the blood.
Clinical Immunology. 2014, 152, 20-24.
Longitudinal T cell-derived IFN-γ/IL-17 balances do not correlate with the disease course in two mouse models of experimental autoimmune encephalomyelitis.
Journal of Immunological Methods. 2013, 398-399, 68-75.
Chapter: When results of T cell immune monitoring match or do not match clinical outcomes of tumor vaccine trials — What more could and should we measure?
The Tumor Immunoenvironment. (CH-32). 2013, 725-740.
Methods and Protocols, Handbook of ELISPOT. 2011, 792, 125-143.
Methods and Protocols, Handbook of ELISPOT. 2011, 792, 173-183.
Methods and Protocols, Handbook of ELISPOT. 2011. 792, 3-23.
Eye. 2012, 26, 872-881.
Cells. 2012, 1, 127-140.
Chapter: Objective, user-independent ELISPOT data analysis based on scientifically-validated principles.
Methods and Protocols, Handbook of ELISPOT. 2011, 792, 155-171.
The Immune Pathogenesis of Experimental Autoimmune Encephalomyelitis – Lessons Learned for Multiple Sclerosis?
Journal of Interferon & Cytokine Research. 2011. 31:907-16.
Clinical Immunology. 2011, 140, 54-62.
American Society of Tropical Medicine and Hygiene. 84(6), 2011. 978–987.
The Polyomavirus BK large T-antigen-derived peptide elicits an HLA-DR promiscuous and polyfunctional CD4+ T cell response.
Clinical Vaccine Immunology. 2011, 18, 815-824.
Clinical Cancer Research. 2011, 17, 3064-3076.
The clinical course of EAE is reflected by the dynamics of the neuroantigen-specific T cell compartment in the blood.
Clinical Immunology. 2010, 137, 422-432.
Involvement of brain-derived neurotrophic factor (BDNF) in MP4-induced autoimmune encephalomyelitis.
Clinical Immunology. 2010, 137, 181-189.
Th1 responses to beta-amyloid in young humans convert to regulatory IL-10 responses in Down syndrome and Alzheimer’s disease.
Neurobiology of Aging. 2010, 31, 1732-42.
ELISPOT assays provide reproducible results among different laboratories for T-cell immune monitoring – even in hands of ELISPOT-inexperienced investigators.
Journal of Immunotoxicology. 2009, 6, 227-34.
Impaired plasmacytoid dendritic cell (PDC)-NK cell activity in viremic human immunodeficiency virus infection attributable to impairments in both PDC and NK cell function.
Journal of Virology. 2009, 83, 11175-11187.
Encephalitogenicity of complete Freund’s adjuvant relative to CpG is linked to induction of Th17 cells.
Journal of Immunology. 2009, 183, 5654-5661.
Journal of Immunotherapy. 2009, 32, 389.
Clinical Immunology. 2009, 131, 288-297.
Cellular Immunology. 2009, 258, 131-137.
Perspective: research highlights at the Case Western Reserve University Center for AIDS Research. Learning from the past and looking toward the future.
AIDS Research and Human Retroviruses. 1996, 12, 1659.
Fundamental differences in the dynamics of CNS lesion development and composition in MP4- and MOG peptide 35-55-induced experimental autoimmune encephalomyelitis.
Clinical Immunology. 2008, 129, 256-267.
AIDS Research and Human Retroviruses. 2008, 24, 1-9.
Antigen structure influences helper T-cell epitope dominance in the human immune re- sponse to HIV envelope glycoprotein gp120.
European Journal of Immunology. 2008, 38, 1231-1237.
Lack of Disease Specificity Limits the Usefulness of in vitro Costimulation in HIV- and HCV-Infected Patients.
Clinical and Developmental Immunology. 2008, 38, 1231-1237.
Chapter: Validating reference samples for comparison in a regulated ELISPOT assay.
Validation of Cell-based Assays in the GLP Setting. (CH 9) 2008.
Making the jump to high throughput microbial detection
Medlab. 2008, 3, 30-32.
Immunogenicity of unprocessed and photooxidized bovine and human osteochondral grafts in collagen-sensitive mice BMC.
Musculoskeletal Disorders. 2006. 7:32.
The secretory IFN-γ response of single CD4 memory cells after activation on different antigen presenting cell types.
Clinical Immunology. 2007, 124, 267-276.
MP4- and MOG:35-55-induced EAE in C57BL/6 mice differentially targets brain, spinal cord and cerebellum.
Journal of Neuroimmunology. 2007, 189, 31-40.
Kinetics and Organ Distribution of IL-17-Producing CD4 Cells in Proteolipid Protein 139-151 Peptide-Induced Experimental Autoimmune Encephalomyelitis of SJL Mice.
Journal of Immunology. 2007, 178, 1372-1378.
Neonatal induction of myelin-specific Th1/Th17 immunity does not result in experimental autoimmune encephalomyelitis and can protect against the disease in adulthood.
Journal of Neuroimmunology. 2007, 187, 20-30.
Granzyme-B production, but not cytokine signatures distinguish recently activated CD8 memory cells from resting memory cells.
Cell Immunology. 2007, 247, 36-48.
Dissociation of EAE protective effect and allergic side reactions in tolerization with neuroantigen.
Journal of Immunology. 2006, 178, 4749-4756.
Dissociated production of perforin, granzyme B and IFN-γ by HIV-specific CD8+ cells in HIV infection.
AIDS Research and Human Retroviruses. 2007, 24, 62-71.
Journal of Infectious Diseases. 2006, 194, 391-400.
Immunologic testing of xeno-derived osteochondral grafts using peripheral blood mononuclear cells from healthy human donors.
BMC Musculoskeletal Disorders. 2005, 36.
Journal of Neuroimmunology. 2005, 170, 105-114.
Transplantation. 2005, 80, 1316-1322.
IL-2 absorption affects IFN- gamma and IL-5, but not IL-4 producing memory T cells in double color cytokine ELISPOT assays.
Cell Immunology. 2005, 237, 28-36.
CD4+CD25+ regulatory T cells control the progression from periinsulitis to destructive insulitis in murine autoimmune diabetes.
Cell Immunology. 2005, 235, 1-11.
Cell Immunology. 2005, 235, 29-38.
Islet-cell antigen-reactive T cells show different expansion rates and Th1/Th2 differentiation in type 1 diabetic patients and healthy controls.
Clinical Immunology. 2005, 115, 102-114.
Methods in Molecular Biology. 2005, 302, 117-32.
Results of an ELISPOT Proficiency Panel Conducted in 11 Laboratories Participating in International Human Immunodeficiency Virus Type 1 Vaccine trials.
AIDS Research & Human Retroviruses. 2005, 21, 68-81.
Increased in vivo frequency of IA-2 peptide-reactive IFNgamma+/IL-4- T cells in type 1 diabetic subjects.
Journal of Autoimmunity. 2004, 23, 45-54.
Journal of Immunology. 2004, 173, 1012-1022.
Selective impairments in dendritic cell-associated function distinguish hepatitis C virus and HIV infection.
Journal of Immunology. 2004, 172, 4907-4916.
T cells recognize multiple GAD65 and proinsulin epitopes in human type 1 diabetes, suggesting determinant spreading.
J Clin Immunol. 2004, 24, 327-339.
CD28 costimulation enhances the sensitivity of the ELISPOT assay for detection of antigen-specific memory effector CD4 and CD8 cell populations in human diseases.
Journal of Immunological Methods. 2004, 285, 223-235.
Deficient IFN-gamma expression in umbilical cord blood (UCB) T cells can be rescued by IFN-gamma-mediated increase in NFATc2 expression.
Journal of Clinical Immunology. 2003, 23, 485-497.
Journal of Immunology. 2003, 171, 3941-3946.
Protective efficacy of anti-Helicobacter pylori immunity following systemic immunization of neonatal mice.
Infection and Immununity. 2003, 71, 1820-1827
Detection of low-frequency antigen-specific IL-10-producing CD4(+) T cells via ELISPOT in PBMC: cognate vs. nonspecific production of the cytokine.
Journal of Immunological Methods. 2003, 279, 111-121.
Enzyme linked immunosorbent spot (ELISPOT) assay for interferon-gamma independently predicts renal function in kidney transplant recipients.
American Journal of Transplantation. 2003, 3, 878-884.
CD4+ and CD8+ cells in cryopreserved human PBMC maintain full functionality in cytokine ELISPOT assays.
Journal of Immunological Methods. 2003, 278, 79-93.
On the same cell type GPI- anchored normal cellular prion and DAF protein exhibit different biological properties.
Biochemical and Biophysical Research Communications. 2003, 303, 446-451
Journal of Neuroimmunology. 2003, 134, 25-34.
Evolution of the enzyme-linked immunosorbent spot assay for post-transplant alloreactivity as a potentially useful immune monitoring tool.
American Journal of Transplantation. 2002, 2, 857.
Diabetes/Metabolism Research and Reviews. 2002, 18, 367-380.
CD4+ T cells recognizing specific antigen deposited in glomeruli cause glomerulonephritis-like kidney injury.
Clinical Immunology. 2002, 104, 161-173.
Journal of Immunology. 2002, 168, 6099-6105.
Clinical Immunology. 2009, 133, 45-51.
Comprehensive determinant mapping of the hepatitis C-specific CD8 cell repertoire reveals unpredicted immune hierarchy.
Clinical Immunology. 2002, 103, 264-276.
AIDS. 2002, 16, 1113-1118.
Production of transforming growth factor-beta 1 (TGF-β1) expression in human monocytes infected with Mycrobacterium Avium at a single cell level by ELISPOT assay.
Journal of Immunological Methods. 2002, 259, 25-32.
Protective anti-Helicobacter immunity is induced with aluminum hydroxide or complete Freund’s adjuvant by systemic immunization.
Journal of Infectious Diseases. 2001, 184, 308-314.
Immunomodulatory effect of extracorporeal photopheresis after successful treatment of resistant renal allograft rejection.
Photodermatology, Photoimmunology & Photomedicine. 2001, 17, 79-82.
Journal of Immunology. 2001, 167, 1353-1361
Staphylococcal enterotoxin-B-induced lethal shock in mice is T-cell-dependent, but disease susceptibility is defined by the non-T-cell compartment.
Clinical Immunology. 2001, 98, 85-94.
Journal of Immunological Methods. 2000, 240, 143-155.
Comprehensive assessment of determinant specificity, frequency, and cytokine signature of the primed CD8 cell repertoire induced by a minor transplantation antigen.
Journal of Immunology. 2000, 165, 12781284.
Quantification of self-recognition in multiple sclerosis by single-cell analysis of cytokine production.
Journal of Immunology. 2000, 165, 1641-1651.
Journal of Immunology. 2000, 164, 5771-5781.
Frequencies of neuroantigen-specific T cells in the central nervous system versus the immune periphery during the course of experimental allergic encephalomyelitis.
Journal of Immunology. 2001, 166, 4757-4764.
Direct visualization of cytokine-producing recall antigen-specific CD4 memory T cells in healthy individuals and HIV patients.
Journal of Immunology. 2000, 164, 3723-3732
Selective peptidomimetic blockers of autoantigen presentation: a novel therapeutic approach to autoimmune disease.
Trends in Pharmacological Sciences. 2000, 21, 79-80.
Journal of Immunology. 2000, 164, 1862-1872.
Journal of Autoimmunity. 1999, 12, 191-198.
Adjuvant-guided type- 1 and type-2 immunity: infectious/noninfectious dichotomy defines the class of response.
Journal of Immunology. 1999, 162, 3942-3949.
Enhanced responses to Mycobacterium tuberculosis antigens by human alveolar lymphocytes during active pulmonary tuberculosis.
Journal of Infectious Diseases. 1998, 178, 1434-1445.
Heat shock proteins and experimental autoimmune encephalomyelitis. II: environmental infection and extra-neuraxial inflammation alter the course of chronic relapsing encephalomyelitis.
Journal of Neuroimmunology. 1998, 90, 149-161.
American Journal of Pathology. 1998, 153, 677-680.
Immunological Review. 1998, 164, 53-61.
Science. 1998, 281, 703-706.
Journal of Experimental Medicine. 1998, 187, 2055-2063.
High-resolution characterization of cytokine-producing alloreactivity in naive and allograft-primed mice.
Transplantation. 1998, 65, 906-914.
Journal of Experimental Medicine. 1997, 186, 1623-1631.
Transplantation. 1997, 64, 292-296.
Journal of Experimental Medicine. 1997, 186, 2039-2043.
Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes-prone mice.
Nature Medicine. 1996, 2, 1348-1353.
Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes.
Journal of Experimental Medicine. 1996, 183, 1561-1567
T cell cross-reactivity between coxsackievirus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele.
Journal of Experimental Medicine. 1994, 180, 1979-1984.
Journal of Experimental Medicine. 1994, 180,1817-1827.
Limited T cell response to donor MHC peptides during allograft rejection. Implications for selective immune therapy in transplantation.
Journal of Immunology. 1994, 153, 938-945.
International Journal of Cancer. 1994, 56, 546-551.
Annual Review of Immunology. 1993, 11, 729-766.
Immunology Today. 1993, 14, 203-208.
Human mature T cells that are anergic in vivo prevail in SCID mice reconstituted with human peripheral blood.
Journal of Experimental Medicine. 1992, 175, 503-516.
Limited B cell repertoire in severe combined immunodeficient mice engrafted with peripheral blood mononuclear cells derived from immunodeficient or normal humans.
The Journal of Clinical Investigation. 1991, 87, 658-665.
Graft-versus-host resistance induced by class II major histocompatibility complex-specific T cell clones.
Journal of Experimental Medicine. 1991, 173, 333-341.
Journal of Immunology. 1990, 145, 2092-2098.
Flexibility of the T cell repertoire. Self tolerance causes a shift of T cell receptor gene usage in response to insulin.
Journal of Experimental Medicine. 1990, 171, 1665-1681.
Acute lethal graft-versus-host reaction induced by major histocompatibility complex class II-reactive T helper cell clones.
Journal of Experimental Medicine. 1990, 171, 1485-1496.
Inhibition of T cell response with peptides is influenced by both peptide-binding specificity of major histocompatibility complex molecules and susceptibility of T cells to blocking.
European Journal of Immunology. 1989, 19, 1071-1077.
Immunology Today. 1989, 10, 132-138
Nature. 1988, 334, 623-625.
Proceedings of the National Academy of Sciences. 1988, 85, 5181-5185.